the historical journey of discovering the genetic connection to type 2 diabetes, epigenetics

genetics epigenetics diabetes type therapy discovery history research genomic genome prevention epigenomic advances insulin beta pancreas markers factors sequencing precision personalized biomarkers testing risk pathways management emerging insights mechanisms variants modifications metabolic autoimmunity immunotherapy stem immunogenetics islet editing crispr-cas9 targets trials expression pathophysiology non-coding epidemiology regeneration hormonal obesity microbiome