sasp. senescent cells and metabolic disease

sasp senescent cell metabolic disease senescenceassociated secretory phenotype insulin resistance liver steatosis muscle atrophy sarcopenia hyperinsulinemia pancreas atherosclerosis aging process chronic inflammation vector diagram research cancer genetic science senescence medical cellular death anatomy apoptosis structure necrosis dna destruction immune tissue oncology genome telomere chromosome tumor damage phagocytosis illness pathology infection metabolism diabetes fat weight obesity obese digestion treatment diet overweight syndrome diagnosis unhealthy conditions agerelated dysfunction senolytics adipose oxidative stress disorders rejuvenation