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procyanidin proanthocyanidin horse chestnut aesculus hippocastanum cranberry juice cinchona cinnamon ceylon cinnamomum persea avocado alligator pear flavanoid supplement pac urinary tract infection prevention uti coli escherichia bladder adhesion cranberries molecule atoms atomic model molecular compound composition chemical chemistry bond structure formula circle circles skeletal line structural vector a2 present number other plants used infarction stylized 2d rendering conventional