inflammaging. hallmarks of ageing. chronic inflammation

senescenceassociated inflammageing mitochondrial intercellular inflammaging inflammation mitochondria proteostasis inflammatory disturbance instability dysfunction compromised alterations senescence microbiome exhaustion epigenetic shortening metabolism hallmarks antiaging autophagy attrition oxidative metabolic senescent secretory phenotype cytokines develops advanced medicine cellular telomere hormonal chronic therapy genomic atrophy histone decline science disease diagram ageing vector muscle immune thymus stress system poster aging drift stem cell sasp