depression and its isolation

depression isolation mental health loneliness depressive disorder social withdrawal emotional struggle self-isolation psychological pain solitary confinement despair state exclusion distress solitude illness depression#39aph39#s impact isolation suffering symptoms seclusion health self-imposed anguish loneliness disconnection effects challenges agony detachment seclusion well-being isolation#39aph39#s toll struggle loneliness#39aph39#s solitude emotions exclusion suffering effect anguish consequences detachment struggles well-being impact disconnection withdrawal#39aph39#s state