crispr-cas9 gene editing complex from streptococcus pyogenes. the cas9 nuclease protein uses a guide rna sequence to cut dna at a

crispr cas cas9 crisprcas9 clustered regularly interspaced short palindromic repeats dna rna virus bacteria gene resistance editing associated nuclease genome pdb4un3 streptococcus pyogenes transactivating sgrna drug cure therapy biotech interference structure peptide protein amino acid molecule polypeptide polymer atoms