coccidioides imitis rupturing spherule with endospores on gms stain

pathology specimen fungus cocci disseminated gms silver stain mycology windborne soil chronic fatigue pink red purple granuloma granulomata granulomatous inflammation biopsy diagnosis coccidioides endospores fungal histology infection infectious microscopic spherule spores tissue sample desert arid pneumonia black round hypoxemia mycosis endemic cell wall rupture rupturing