3d image of leukotriene a4 skeletal formula

leukotriene a4 eicosanoid inflammatory mediator leukocyte arachidonic acid essential fatty eicosapentaenoic epa arachidonate 5-lipoxygenase lipid signaling autocrine paracrine histamine prostaglandins bronchioles asthma allergic rhinitis antagonists mast cells eosinophils neutrophils monocytes basophils glutathione inflammatory inflammation immune system autoimmune disease response bronchoconstriction dementia anaphylactic shock metabolite metabolism biosynthesis cycle mechanism biosynthetic intermediate biogenesis precursor synthesis derivative bioprecursor metabolic enzyme endogenous 3d